Serena Hotels is a hospitality company which operates up-scale hotels and resorts in East Africa, Southern Africa and South Asia.

As of 2023, Serena comprises a collection of 34 luxury resorts, safari lodges, and hotels, which are located in East Africa (Democratic Republic of the Congo, Kenya, Tanzania, Rwanda, Uganda, and Mozambique) and Central and South Asia (Pakistan, Afghanistan, and Tajikistan).

The Serena Hotels Group trades under the name Tourism Promotion Services (TPS Serena). The company is listed on the Nairobi Stock Exchange (NSE), where it trades under the symbol TPS. The largest shareholder (45%) is the Aga Khan Fund for Economic Development (AKFED), with a further 4% owned by the Aga Khan University Foundation.